Hi Soundman,
I think it is extremely doubtful, unless someone has already written the software (similar to that which is required for the Smooth Stepper).
However, If your axis driver cards accept 'step and direction signals' then there is always the possibility you could use a breakout board and parallel cable from your PC and tap into the driver cards at the appropriate points - Thus using Mach3 for the control.
Home and limit switches are another problem but not unsurmountable.
Tweakie.
ps. You shout all you like - no worries.