Hi, Wayne
Sounds like you have a work offset issue, Look on the Offsets page, Click the Machine Coord's Button, Do the DRO's change values ?
If thy do, change to your Program Run Screen, Ref-All-Home then click the Machine Cood's for "no red outline state", then Zero XYZ.
This is easy to get into if you say yes to Fixture Offset Save Yes/No after shutting down Mach.
Hope this is It, Chip
Tried to Skype you no one home.