Hi. First post so please be gentle. 
..and please excuse my bad english.

I can not find how to change direction of the work area?

When I run the machine to home pos, it goes to the lower right corner, which is correct.
But when I run a job I have to run to the upper left corner and put zero because the job would go toward + and not -.

Anybody know how to change this?
see attached image.

Many thanks

I think you are going to get lots of differing views on this (perhaps controversial) topic.

Whilst the medium to upper range CAD/CAM software allows the home position (X0, Y0) to be in any corner (including centre) the basic CAD/CAM packages generally only allow the home position to be in the bottom left corner.

In my opinion, your machine should be set-up with X0, Y0 in the bottom left corner of the work-piece with +X moving the cutter to the right of the work and +Y moving the cutter to the rear of the work ( Axis direction can be changed by altering the Direction Active Low state in Config. / Ports & Pins / Motor Outputs ).

Tweakie.

Thanx Tweakie for your answer.

humm,  controversial topic??
Is it possible for you to suggest new topic so I can change, it is not meant to offend anyone. this is because my bad English. 

I bought a broken multicam machine that I built for MACH 3.
This has its homing in the lower right corner.
I have been using Sketchup with sketchucam.
When I export gcode after moving the zero point to the other side of the job, it becomes empty in gcode. but I can try to move the home position to the lower left corner, so maybe it will be better.

but if I change the Direction Active Low state in the Config. / Ports & Pins / Motor Outputs. it will be mirrored then?

Many thanks for the reply

Absolutely nothing wrong with your English sir - it is just my opinion that the topic is controversial only because many people will have different views regarding the origin and home positions.

but if I change the Direction Active Low state in the Config. / Ports & Pins / Motor Outputs. it will be mirrored then?

If +X moves the cutter to the right of the workpiece and +Y moves the cutter to the rear of the workpiece then it will not be mirrored.

Tweakie.

On your sketches, both appear wrong to  me - the Y is wrong in the first and the X is wrong in the second - this is of course assuming that machine home would be front-left corner.

The corner it moves to when doing a home does not really matter as it can be set to home on the right but in reality it will place the real home/zero position to the left - read up on home switch offsets

Likewise the home position chosen in CAM does not matter - what DOES matter is that you set the same home point on the material as was chosen in CAM or odd things can happen.

As Dave says, you must use a standard right hand coordinate system, which neither of the ones you show are.

Hi. Now I got it to work. I and as you say. I was wrong about the coordinates.
Now I home at the front right corner and x+ takes me to the far right and y+ to the left 

But I can't get the homing with my slave axis to work. 
My slave A axis stops when the X is home. So if The x i not straight I won't compensate for this..

I tried to change to refcombination(9) but not.
Are they any script the home them separately?
Starts at the same time and stops at the sensor?

Thanx 

do you have two home switches on the slaved axis - you need one at each side

Yes I have one for a and one for x.
They are tested and dedicated in ports and pins.

In General Config, make sure that Home Slave with Master is NOT checked.