My router is big. I want the longest run to be the "X" . So I set it up with the 0,0 at the closest left in front of my router. "Y" runs left to right and "X" runs front to back. I can't walk around my router. I am the only one that runs the router. I use Ctu2D, When I first started to use it all my text was mirrored. I tried to find a way around that to no avail. So now after I have my dxf set up the way I want it in Cut2D I flip the image and then run the tool paths. Kind of a pain, BUT, it works and now I don't give a second thought, it's just automatic with me. To run the files without flipping them I have to orient my work on the router at a point I can't get to easily.
I know this doesn't help, but you might have to live with the problem like I have to.
Dave