Hi Martin,
Sorry to hear that you are having problems getting everything to run correctly.
Just to be sure - you have set motor directions so that the origin (X zero – Y zero) is with the cutter at the bottom left hand corner of the work ??
It’s open to debate but this is what I would suggest…
Initially, I would recommend setting up your motor tuning steps per unit using 1/8 micro-stepping (there is little or no advantage in going to 1/16).
Set your motor current so that the motors will run warm to the touch but not so hot that you cannot hold your hand on them with comfort.
Check your wiring runs…
Inputs (limit / home switches, e-stop etc.) should be connected using shielded wiring, with the shield connected to a single point earth at the controller end. All other earth connections, including the machine frame, should connect to this single point earth. (If your wiring looks like a rats nest then that is asking for problems).
Mains wiring should be routed separately to the signal wiring (Inputs).
Perhaps posting a picture of what you have at present (layout of the wiring) may help with suggestions.
Hope this is of assistance,
Tweakie.