Do you have G61 at the start of your program?
For the Run from Here, you can either click on the code and use the up/down arrows to get where you want to start, or you can enter a line number in the DRO and hit enter on your keyboard. When you then click the run from here button it should run through the code and stop at the line you have chosen, once thats done click the start button and a box should appear asking you to confirm the initial move, click OK, it will move then hit the start again and your program should run.
Hood
edit
Too slow in typing as usual LOL