Hi Jeff,
Thanks a lot for your answer.
I think the problem is my screen set.
I did it with machscreen and durind making machscreen told me the screenset was corrupted, but load it correctly.
So from that moment mach3 using the new screenset has very strange behaviour, in fact it doesn't run correctly the button script

and any modify is not sure saved.
In my opinion is possible mach3 saves any change at the quit, but I can't quit correctly.
I tried to install MachStdMill and it seems to quit right, but after if I try to load my screenset mach3 is unable to turn on the spindle and give me an error, so I must reinstall mah3 again.
My situation is complicated i think,

Thanks a lot again, regards
Bruno