Heres what we use 10 hours a day, cutters last months.
Okuma 4VA, big ridgid tool making cnc.
6000 rpm, thats as fast as it goes. Always climb milling.
Ultra synthet (with water) lubricant, we used to use soluble oil/water emulsion. Always flood coolant.
Nearly always solid carbide uncoated tools. Sometimes brazed carbide router bits for special profiles.
Roughing with 16mm rmr, three flute, Sandvick, tagutec, or hanita, stelram. feed 2500mmpm, cut about 8mm deep, full width.
Facing with sandvick 8 tip, dia 125mm, aluminium wiper inserts, 2500rpm, 2500mmpm.
Finish with 2 flute carbide end mill, 6000rpm, 1000mmpm (40ipm), 0.2mm stock finish cut, 5mm step depth for profiling.
Some cutters seem to work better than others. We find 6061-T6 or 6061-T651 to machine quite well. 5005 is horible, 5083 OK and 7075 good.
HSS tools do work at 1/3 of the rpm of carbide but need to be short to be stiff enough.
We always use the shortest tools practical and on deep parts we often use a short tool then a long one for the deep parts at lower feed rate and depth of cut.
Good luck.