Now I see,As I read the Manual, M3M4 is just used to enable the unit. But if that is so what is the OTHER enable signal doing? UNless it is the other end of the enable circuit?

The direction is controlled by the DIR pin.
Do all of the LEDs work correctly? If so Maybe a problem with your FLIP/FLOP relay(CW,CCW)
Does it run in the same direction each time you run it? CW always? CCW always? or does it change sometimes(sticky relay)?
Let me see if I have the problem correctly. When you Command a M3/M4 the spindle starts up. THe S command will change the speed. M5 will stop the Spindle. But using M3-4 does not change the direction?
Is that correct?
(;-) TP