Or do this, which sets the zero position, but doesn't actually move it to zero. Just use the appropriate X and Y offsets.
XOffset = 3.43 'X offset from laser crosshair to spindle
YOffset = 4.322 'Y offset from laser crosshair to spindle
SetOEMDRO(800,XOffset)
SetOEMDRO(801,YOffset)
Sleep(125)