I badly need some help, and the search function didn't turn up what I need. Background: Win7 Ultimate 32bit box dedicated exclusively to running my Zenbot with a PCI interface to the cnc box, worked fine for a year, let sit for 6 months and got a project doing a print catalog and wood trophies for a livestock show. My dedicated graphics PC went south and I had to do the catalog on my cnc control PC. When I attempted to print the catalog to my USB printer a dialog box appeared stating something like...port being used by another device do you want to ...

Being way behind deadline I clicked ok.
2 weeks later I loaded up my gcode and l discovered the PC will not communicate with the cnc machine

. Mach runs the project, you can follow it on the screen as it cuts, but the machine just sits there. When I initially installed the PCI card I did not install the included drivers (as per forum advice, use the Mach drivers) and don't want to now.
How can I reestablish communications without uninstalling/reinstalling Mach and losing all my configuration settings, I am getting
way behind on this project and I'm not sure if just changing the port address will fix this, and I truly don't have a lot of cnc experience.
Thank you in advance for your time and assistance,
jim