I presume that you have solved this by now but since I am encountering the same problem as I develop my custom plugin I also presume it means that you have a corrupted plugin in your Mach3\PlugIns directory. You can move them all out and verify that you can start Mach3 then move them back in one at a time to see which (if any) is causing the problem. At this moment I have no idea what the error code means and I can't fin't the error codes documented anywhere.