It all depends. I do everything from thick tool steel with a 3/4" end mill to v carving acrylic .013" deep. Because of the heavy tool loads I run a much lower accel than I could get away with on the light stuff. Hey, I just thought of something indirectly related to something myself and another member have talked about, different profiles. This guy is sharp. I won't mention his name but his initials are Hood.
One for light and one for heavy tool loads. I would go as high as I could without skipping steps. The higher the accel. the better, or easier tuning in your cv mode would be. I think. I think I remember reading somewhere, keep bumping up until you just start to loose steps and back off 10%.