After pulling my computer and Plasma Table out of storage after 2 years I reloaded Windows 7, Loaded Mach3 only.  Rebooted after install and then proceeded to setup my inputs and outputs with no issues.
Overnight the computer shut off.  Now when I try to boot the computer it just repeats the startup screen.

I've repeated this a few times with a few different builds of Mach3 and with the registry patches loaded through the CMD Prompt.

Any idea. I want to avoid changing any hardware if I can as when I stored it before my move everything worked great and I knew the ins and outs of the program/electronics on my build.

Definitely it is your hardware problem.
Could be power supply, electrolytic capacitors on motherboard and, maybe, poorly seated cooler on CPU (likely needs a change of thermal paste).