It is certainly possible but most existing CAD/CAM software (which produces the necessary GCode) would program separate X and Y movements so you would probably have to write your own CAD/CAM software to take advantage of the 'same direction' / 'opposite direction', combined X-Y stepper rotations.
I don't really see any advantage to using the H-Bot configuration as opposed to conventional X - Y movement but perhaps there is one.
Tweakie.