I have been Beta testing the smooth stepper for 2 or 3 months, have a keyboard, touch pad, touch screen, wireless network adapter and the SmoothStepper all in USB and have not had a problem. I think there are over 20 Beta testers and as far as I know no one has had such a problem.
If the Smooth Stepper had a communication problem then it would fault mach with an error so dont think there will be issues.
To be honest I was a bit sceptical like you are, because I have had printers, scanners etc connect and disconnect when on USB but there doesnt seem to be that problem with the SmoothStepper, maybe Greg or some of the more technically minded can give you more info or assurances.
Hood