Hi all,
Simon,
please try the following.
note all your settings in mach on a sheet of paper ( or make a screenshot )
delete the old XML's ( or move it to an other place )
reinstall Mach3 ( be sure to do it as recommended )
reboot PC
important: DO NOT load an old profile ( XML)!
There will be a new fresh Turn Profile
DO NOT load an other screenset as the standart !
type in your settings and test the result.
It looks to me that your XML corrupted the system ( Mach3)
at least it did mine. grrrr

Alex