I am not sure what you are meaning
The zero button at the side of the axis DROs will zero the work offset (whichever you are using, G54, G55 etc)
It does not matter whether you are viewing Machine Coords or not, the offset will zero. Machine coords will not change, you can only zero them by homing (not strictly true but for this discussion it is
) So if you are showing machine coords and you zero an axis you will not see the DROs change but when you go back and view the offset DROs (press machine coords button again) you will see they have changed to zero.
Hood