Filipe,
I am not sure what you want. There is Design software out there, that based on a routing, will give you the detailed duct drawings ( not sure if some of them will then take the iso and then convert it to sheet metal layout).
Some will even size your ducting. That said some of them were add ons for CAD programs like AutoCad or Microstation but they work with the high end products of 3D. At Work we use high end design managment tools that do all that but a single monthly seat is more than that.
RICH