If you look at the Mach screen, normally in the bottom right hand side it will tell you what profile you are running.
Open up the mach3 folder (normally c:\mach3\) and look for your profile with the same name (for example Mach mill.xml, or more correctly for you, plasma.xml), copy it to your desktop, then change its name to say... moccasin1.xml... and upload it.
The XML file provides all of your settings in a raw file to mach3, the file is loaded at startup of mach3.
Unfortunately it can become corrupted on odd occasions .... which may be what has happened to you.
Mach is a dumb piece of software, if the XML says port 1, port 2 is for output 1, and for whatever reason it is changed to port 1, pin3... it will use that.... also... on the ports and pins tab, 2nd last tab, think it's mill settings, it says m3 uses output 1 for example, and output 2 uses m4 (top left hand side of the tab, if you swap these two settings over, your machine will probably work fine...... probably)
It may also be the sheetcam post processor......if you open up sheetcam, and go to the machine tab (think it's under settings, top line), it will allow you to open up the post processor to edit it..... in hindsight, this may be your problem because when you want to run your torch, it moves off to one side (which is the engraver offset... and fires the torch....)
Basically these three bits tell mach3 what it needs to know to do stuff in the right order.
Hence if you upload the profile, I'll take a look at it.
Ill look at the tap file later (must admit should have looked at it earlier...., as it will probably tell me if it's the post processor)