Success..............M06 macro is now working.
Interestingly, the keyboard is working correctly now, also probing appears to now work (correctly!). Don't know what was going on before................
Basically, as suggested, I deleted all of Mach4 including profiles, and reinstalled and setup from scratch. Got the sim plugin only working and tested, then installed, configured Darwin and Mach4 - testing at each step and loging results. Finally a full test.
Thanks blockhead, Daz and others for suggestions and time - I greatly appreciated your feedback.This forum is definately a great resource.
Richard