Hi FredMazak,
I'm running a Csmio ip-s controller on a 64 bit windows 7, and both Mach3 and 4 run fine. I have several VB scripts running without any problems on Mach 3. Mach 4 has a small glitch with m3/m4 not starting the spindle. But the spindle on/off button works ok. M3/M4 sends the 0-10v to drive but it doesn't activate the output.
Hope this helps.
Alan