I find entering numbers in the DROs rather inconvenient comparing to how it used to be in Mach3 where a single click would highlight the whole number. Now you have to highlight the the number with the mouse. While it's the typical Windows way to do this, I think it is not suitable for a machine control. When I do it in the web browser or google, for instance, sometimes the whole string doesn't get highlighted and there is a character left (sure it happened to you a few times) and then you notice the mistake when you see the wrong search result. In a machine control this type of mistake could have more devastating outcome. Also this way of doing things is completely not suitable for a touch screen.
And speaking of touch screens, there is the very handy auto calculator that pops up in Mach3 and is very handy with touch screens. Eliminating wondering between the keyboard, mouse and screen.
Also posted this one earlier but it seems it slipped unnoticed:
Under Config -> Homing/Softlimits, mouse clicking in the Soft Enable column doen't toggle states. You have to input from the keyboard '0' or '1' to toggle states.